Neonatal appendicitis in term and preterm babies

The aims of this study are to present the cases of two newborns with perforated appendicitis in newborn intensive care unit in a 3-months period, and discuss the pathophysiology of neonatal appendicitis

Relationship between endometrial thickness and in vitro fertilization-intracytoplasmic sperm injection outcome

This study assessed the relationship between endometrial thickness on day of human chorionic gonadotropin [hCG] administration and in vitro fertilization intracytoplasmic sperm injection [IVF-ICSI]. This prospective cross-sectional study included a total of 593 women. Patients were treated with either the agonist or antagonist protocol according to the clinician's and patient's preference. Endometrial thickness on the hCG day was measured by transvaginal ultrasonography [TV-USG]. Patients were divided into four groups according to endometrial lines, as follows: <7 mm [group 1], 7-10 mm [group 2], 10-14 mm [group 3], and >14 mm [group 4]. Implantation rate [IR], clinical pregnancy rate [CPR], and ongoing pregnancy rate [OPR] were significantly lower in group 1 than the other three groups [p<0.05]. However, there was no significant difference among groups 2, 3 and 4. Although the endometrial line in the agonist protocol was higher than in the antagonist protocol, the difference was not statistically significant. The chance of pregnancy appears to be lower in individuals with endometrial thickness less than 7 mm compared with those of higher value

Efficacy of the local endometrial injury in patients who had previous failed IVF-ICSI outcome

The latest studies reported that local endometrial injury is a useful method to improve the success of IVF-ICSI outcome. To assess whether local endometrial injury occurred by Pipelle in the spontaneous cycle could improve implantation rate, cleavage rate, and pregnancy outcome in the subsequent IVF-ICSI cycle in patients who had recurrent IVF failure. An endometrial biopsy was performed on day 21st in 41 patients as intervention group in this retrospective cross-sectional study. The control group contained 42 women. Implantation rate was 22.5% and 10.5% in intervention and control group, respectively and this difference was found to be statistically significant [p=001]. Pregnancy rate was 43.9% in the intervention group and this parameter was significantly lower in control group [21.4%] [p=0.03]. Local endometrial injury in the nontransfer cycle increases the implantation rate and pregnancy rate in the subsequent IVF-ICSI cycle in patients who had previous failed IVF-ICSI outcome